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Gwenaëlle Gravis Selected Research

Tyrosine Kinase Inhibitors

1/2022Nivolumab, nivolumab-ipilimumab, and VEGFR-tyrosine kinase inhibitors as first-line treatment for metastatic clear-cell renal cell carcinoma (BIONIKK): a biomarker-driven, open-label, non-comparative, randomised, phase 2 trial.
1/2019Vitiligo Adverse Event Observed in a Patient With Durable Complete Response After Nivolumab for Metastatic Renal Cell Carcinoma.
2/2012Complete remission with tyrosine kinase inhibitors in renal cell carcinoma.

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Gwenaëlle Gravis Research Topics

Disease

16Prostatic Neoplasms (Prostate Cancer)
01/2022 - 06/2004
11Neoplasms (Cancer)
01/2022 - 11/2006
10Renal Cell Carcinoma (Grawitz Tumor)
01/2022 - 07/2011
4Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
01/2021 - 12/2014
4Carcinoma (Carcinomatosis)
11/2018 - 11/2006
3Neutropenia
01/2022 - 10/2010
3Fatigue
01/2022 - 01/2012
3Neoplasm Metastasis (Metastasis)
01/2018 - 04/2015
2Febrile Neutropenia
01/2022 - 10/2010
2Hypertension (High Blood Pressure)
01/2022 - 01/2022
1Massive Hepatic Necrosis
01/2022
1Heart Failure
01/2022
1Thrombotic Microangiopathies
01/2022
1Digestive System Diseases
01/2022
1Seminoma
01/2022
1Liver Failure
01/2022
1Vitiligo
01/2019
1Vomiting
01/2017
1Thrombocytopenia (Thrombopenia)
01/2017
1Nausea
01/2017
1Lymphopenia (Lymphocytopenia)
01/2017
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
03/2016
1Lung Neoplasms (Lung Cancer)
07/2015
1Testicular Neoplasms (Testicular Cancer)
12/2014
1Nonseminomatous germ cell tumor
12/2014
1Edema (Dropsy)
01/2013
1Esophagitis
03/2012
1Hemorrhage
03/2012
1Constipation
01/2011
1Kidney Neoplasms (Kidney Cancer)
01/2011
1Hypothyroidism
01/2011
1Asthenia
01/2011

Drug/Important Bio-Agent (IBA)

10Docetaxel (Taxotere)FDA Link
01/2022 - 06/2009
7AndrogensIBA
01/2022 - 11/2006
4NivolumabIBA
01/2022 - 01/2019
3Prednisone (Sone)FDA LinkGeneric
01/2022 - 10/2010
3Sunitinib (Sutent)FDA Link
01/2022 - 07/2011
3Carboplatin (JM8)FDA LinkGeneric
01/2022 - 12/2017
3Tyrosine Kinase InhibitorsIBA
01/2022 - 02/2012
3IpilimumabIBA
01/2022 - 01/2019
3Cisplatin (Platino)FDA LinkGeneric
01/2022 - 03/2016
3Hormones (Hormone)IBA
10/2021 - 10/2010
3Pharmaceutical PreparationsIBA
01/2021 - 10/2010
3PlatinumIBA
11/2018 - 01/2015
3GemcitabineFDA Link
01/2017 - 01/2015
2Etoposide (VP 16)FDA LinkGeneric
01/2022 - 07/2020
2Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2013
2Axitinib (AG 013736)IBA
01/2020 - 10/2014
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2020 - 07/2011
2Immune Checkpoint InhibitorsIBA
01/2019 - 11/2018
2Prostate-Specific Antigen (Semenogelase)IBA
01/2016 - 07/2015
2EstramustineFDA Link
07/2015 - 01/2012
2Proteins (Proteins, Gene)FDA Link
01/2013 - 11/2006
2Mitoxantrone (Novantrone)FDA LinkGeneric
01/2013 - 10/2010
2taxaneIBA
07/2012 - 10/2010
2cabazitaxelFDA Link
07/2012 - 10/2010
1abirateroneIBA
01/2022
1Lipase (Acid Lipase)FDA Link
01/2022
1cabozantinibIBA
01/2021
1Poly(ADP-ribose) Polymerase InhibitorsIBA
11/2018
1atezolizumabIBA
01/2018
1vinflunineIBA
01/2018
1Paclitaxel (Taxol)FDA LinkGeneric
01/2018
1Taxoids (Taxanes)IBA
01/2018
1Alkaline PhosphataseIBA
01/2017
1Transaminases (Aminotransferases)IBA
01/2017
1Alanine Transaminase (SGPT)IBA
01/2017
170-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA
01/2017
1Leukocyte Immunoglobulin-like Receptor B1IBA
01/2016
1Abiraterone AcetateIBA
04/2015
1Trastuzumab (Herceptin)FDA Link
01/2015
1SaltsIBA
01/2015
1Fetal Proteins (Fetoprotein)IBA
12/2014
1Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
12/2014
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
01/2013
1Nuclear Proteins (Protein, Nuclear)IBA
01/2013
1rilotumumabIBA
01/2013
1Biological ProductsIBA
01/2013
1Monoclonal AntibodiesIBA
01/2013
1Adrenal Cortex Hormones (Corticosteroids)IBA
03/2012
1CoagulantsIBA
03/2012
1Interferon-alpha (Interferon Alfa)IBA
07/2011
1Bevacizumab (Avastin)FDA Link
07/2011
1temsirolimusFDA Link
07/2011
1Thyroid HormonesIBA
01/2011
1TubulinIBA
10/2010
1DNA (Deoxyribonucleic Acid)IBA
11/2006

Therapy/Procedure

13Therapeutics
01/2022 - 10/2010
10Drug Therapy (Chemotherapy)
01/2022 - 06/2009
9Castration
01/2022 - 06/2009
3Immunotherapy
01/2019 - 06/2015
2Lymph Node Excision (Lymph Node Dissection)
12/2014 - 01/2012
1Radiotherapy
01/2022
1Investigational Therapies (Experimental Therapy)
10/2021
1JET protocol
01/2021
1Nephrectomy
01/2019
1Cryosurgery
01/2019
1Duration of Therapy
04/2015
1Aftercare (After-Treatment)
10/2010
1Prostatectomy (Retropubic Prostatectomy)
11/2006